Acuvue Oasys for Astigmatism 6 Pack contact lenses are disposable contact lenses meant to be worn for up to 2 weeks and you have the option to wear them as daily lenses or wear them day and night, without taking them out at night, for up to 7 days. When the contact lenses are taken out, take care of them properly and clean and store them overnight. Don't forget to replace them after 2 weeks and get a fresh pair. Not everyone is can wear contact lenses overnight, please consult your optometrist whether Acuvue Oasys for Astigmatism 6 Pack is suitable for you.